No, I would not recommend mixing the two languages ....
If you really must, do a search online, I'm sure there are some Perl modules that allow you to talk to a Windows host. My guess is, some type of WMI call to Windows host to execute a PowerCLI script.
The other option, setup a Windows VM and have PowerCLI installed and then use VMware VIX API which is for guest management and send the commands or have it execute a specific script via Perl bindings to VIX API - http://www.vmware.com/support/developer/vix-api/
=========================================================================
William Lam
VMware vExpert 2009,2010
VMware scripts and resources at:
Twitter: @lamw
Getting Started with the vMA (tips/tricks)
Getting Started with the vSphere SDK for Perl
VMware Code Central - Scripts/Sample code for Developers and Administrators
VMware Developer Community
If you find this information useful, please award points for "correct" or "helpful".