To me that means yes, VMware should know what OS' do and do not support it right now and have that published.
I am also a bit surprised that this is not know, but to find out I did some manual work to find out.
Depending on the selected guest operating system the selection on the VM:s option tab "Memory/CPU Hotplug" will either not be visible at all or only allow certain combination. It is easy to see if switching between setting the guest on the General Option to Windows 2003 standard = not visible, Windows 2003 Enterprise, visible but only RAM hotadd, Window 2008 = CPU and RAM hotadd.
So by doing some testing I thought I should be able to spot this by creating a dummy VM and testing different guest operating systems and watch the changes on the "Memory/CPU Hotplug".
By these tests I have observed that no version of Solaris, Netware, Freebsd, OS/2, SCO, RH Linux 5, Suse Enterprise, Debian, Asianux or Ubuntu has the CPU hot remove option. Both 32 and 64 bits version tested. Not available on the more generic "Other 64 bit" guest or "Other Linux 2.4x or 2.6x" guest either.
I already know no Windows version is capable of this, so the conclusion seems to be that no guest operating system at the moment actually supports this, and that this option is useless at the moment, but could perhaps be introduced in a later vSphere release.