The CPU-series is at the bottom of the cut-off list for CPU support, but for the current major it is still supported so it is very likely that you will not have to worry for 8.0 U1/U2/U3 and so on. If there were to be an 8.5/8.7/9x+ versions then it is very likely that the CPU would fall out of support.
Current support statement from VMware for the Intel Xeon E5-2600-v4 Series: VMware Compatibility Guide - CPU
The hardware architecture for the Xeon E5 2650-v4 is "Broadwell EP"; starting vSphere 8 VMware has already added other "family-members" of the "Broadwell"-family to the Intel CPU Discontinuation List for that release. As "Broadwell-DT" and "Broadwell-H" are already dropped support-wise it is probable that "Broadwell EP" will follow in the next release.
For reference you can view the tables here:
Updated Plan for CPU Support Discontinuation In vSphere 8.x Release (82794)