Having a fresh mind after the weekend helps.
Here were the connection refusals; I attached different log snippets in my previous post.
Aug 27 11:35:59 iscsid: connect failed (111,Connection refused)
Aug 27 11:36:01 iscsid: connect failed (111,Connection refused)
Aug 27 11:36:01 iscsid: connect failed (111,Connection refused)
The messages log doesn't reveal much more; I unfortunately expect that the issue lies beyond the ESXi host. It doesn't look like EMC has certified the use of any Iomega NAS/SAN arrays for use with VMware ESXi. I'm not privvy on the details as of why not; you could inquire with EMC/Iomega to find out if there are problems, or if they simply have not completed the process. Single controller support is possible when used with ESX, and with firmware 2.1 and above.
Sorry I can't be of much more help; I'd suggest working with EMC/Iomega and giving VMware Technical Support a call if it's deemed an ESX host issue.