Correct re replication etc, and also HA can protect the VC also FT capable in v6.
Key really is to backup and if there are issues that cannot be fixed via a VMware support request, then you have the backup available to you.
Yes, the VC is required for certain management functions but most important ones can be completed directly by logging into the vSphere client to each host. Not ideal but this method is available until the VC issues are resolved.
A combination of backup and replication is the best option here as then you can recover in case of site failure and in case of VC corruption / OS issues etc