I'm using a Thecus N8800 (FW 3.05.02.2) with 8x2TB HDDs as an NFS datastore for VMware ESX 4.1 Update 1 to store very low IO VMs, or temporarily Inactive VMs. I also use the N8800 NFS datastore to hold ISO files for installing stuff. Since the N8800 RAID is limited to 5TB, I broke the 8 drives into two RAID-5 arrays and use one to hold ISOs and the other to hold VMs. The N8800 (plain) doesn't have much horsepower and this firmware version doesn't allow load balancing across both NIC ports to work, so it's easy to overload the NAS box CPU or network channel, but that's what you get in a low end NAS device.
To set the N8800 to work as NFS: Open System Network, NFS and Enable NFS (it's disabled by default).
Open Storage, Share Folder and create a folder to share as NFS. (Take note of the Mount Point information since this will be used when adding the NFS datastore to ESX (aka Folder field below).) Click NFS tab and Add the network that will connect to your ESX hosts NFS network (created below). Remember, to help with your security, you can also just specify the individual hosts. Click NFS tab and Edit the NFS network to set Privilege to Writable, OS Support to Linux, and finally ID Mapping (mine is set: All User on guest system will be mapped to anonymous user (nobody:nogroup) on NAS.) which doesn't have any security but I counter that by building a dedicated network and allow only authorized NFS devices on it.
Using vSphere Client, on each ESX host(s): Select Configuration tab, and add a VMkernel to a vSwitch. (For best performance and security, create a dedicated vSwitch with at least 1 pNIC port, and add the VMkernal to the dedicated vSwitch). Assign an IP Address to the VMkernel vNIC that corresponds to what you allowed on the N8800 NFS network.
Using vSphere Client, on each ESX host(s): Select Configuration tab, and the Storage. Choose Add Storage, then select Network File System option. In the Properties screen, put the IP address of the N8800 in the Server field, as golddiggie described above, in the Folder field put /raid0/data/SHARE_NAME
That's about all there is to it.