High CPU Ready Time values means thats your VMs is struggling for CPU cycles, this are often a result of CPU over commitment.
For example
If you have one ESXi host with a total of 16 cores and 6 VMs with 4 vCPU each and all of the VMs are requesting CPU you will end up with higher CPU ready times as VMs need to wait for the needed amount of CPU cycles before it can start processing.
If high CPU values actually have an negative impact on you environment depends on the applications running on the VMs.
A VM with twice the vCPU also requires twice the CPU cycles to perform the same type of operation as a VM with just one vCPU
Generally a value of 5% CPU ready times is consider OK but to actually see hoe many percent ready times you have you need to make some calculations, VMware have an excellent KB for that
VMware KB: Converting between CPU summation and CPU % ready values
In the end, never give a VM a bunch of CPUs "just in case of", instead give it CPU when it actually requires it.