disabling second nic on VM portgroup

[tdubb123]

I got a portgroup on a vswitch with VM running. It has dual nics in active/active config (vmnic4/vmnic5).

If i disable or remove vmnic5 from the vswitch, would there be interruption to existing VMs? 

I need to do this because i have a faulty cable/module i need to replace to a fabric interconnect on Cisco UCS going to the B side. 

[kgmartin]

tdubb123,

The short answer here, in my opinion, is no, nothing should be interrupted short of a missed ping.

However, that is assuming that everything is configured correctly.  You have one connection to FI-A and one to FI-B, i.e. vmnic4 is using a NIC/VNIC that is connected to A and vmnic5 is connected to B (or vice versa).  Teaming in the vswitch/port group is correct?  Assuming this is a rack mount server connected to the FI's so if everything is configured correctly you should be able to lose an FI port, a cable or a full FI and still maintain communications with the systems.

Another option would be to move all VMs off of this host, assuming you have a VMware HA cluster and enough resources to move the machines and put the host in maintenance mode and then make the repairs.