heres the reposnse from my network guys - maybe you can relate this to your environment ..
CDP info works fine in Site1 but not in Site2 on trunk interfaces because of the global command on the server farm switches "vlan dot1q tag native".
This command is used to tag the native VLAN egress traffic and drop all untagged ingress traffic.
For a reason I don't know, the CDP info packets exchanged between the physical switch and the virtual switch are not tagged and because of the above command they are all dropped.
Possible options to fix the issue :
1) Create new vlan and configure it as native on the ESX trunk interfaces
2) Remove the global command from all server farm switches - Need to identify if this is a standard command or not
Seems to be issue with a global command ??? Hope it helps :smileywink: