Hi Muhamad,
Thanks for using the Broadcom Community!
Unfortunately not, the On Prem SEPM manager only supports SQL Express and SQL Server per below:
https://techdocs.broadcom.com/us/en/symantec-security-software/endpoint-security-and-management/endpoint-protection/all/release-notes/system-requirements-for-v53308029-d69e1453.html
NOTE: For the specific versions / types of SQL Server required see the techdoc above.
Thanks,
Russ_V