Hi
Hope you do a Automic REORG and a DB reorg on a regular basis.
You can check the DB performance and responsetime (DBA)
And have a look at (any) WP log - Message U00003533 for a performance value.
An indicator for a slow DB is recurring message in WP and CP logs:
===> Time critical DB call!
Don't worry, if this message appears once in a couple of hours thats not an issue.
cheers, Wolfgang