Hi Nuno,
Yes, it is possible.
If you have the Desktop Client for CAWA DE, on the right-hand-side, you will find "Monitoring" under the "Palette".
Here, you will find the "File Trigger" job type, which lets you configure a trigger based on the following file actions/statuses:
- Create
- Update
- Delete
- Expand
- Shrunk
- Existing
- Non-Existing

Hope this helps!
Thanks,
Avinash