How big is the GHO file? If it is >4Gb, are you deploying from a local NTFS drive?
Also, you do not mention what version of Ghost you are using. Older versions of Ghost cannot handle deployment of a file >2Gb from a network share.
Remember that when dealing with a problem, especially when urgent, it is VERY important to supply as much information as you can. The version of Ghost is very important, also the version of operating system you are deploying to, and increasingly, whether your bios is set to UEFI or the MBR legacy configuration.
If you are restoring from a USB-3 drive installed in a USB-3 port, and are using Win PE, do you have the correct drivers loaded in Win PE to allow access to the USB-3 port ? If you have a USB-2 port, try that instead.