Thanks for taking an interest guys.
Just in case you can't get site of the link that Franck posted, here's an extract
ESX iSCSI initiator limitations
SnapDrive supports the use of ESX iSCSI initiators, but there are some limitations you must keep in mind.
SnapDrive does not support iSCSI session management using ESX iSCSI initiators.
You can add targets from the initiator list during LUN creation and connection.
Multipathing using both FC HBA and ESX iSCSI initiators is not supported.
Multipathing using both Microsoft iSCSI Software initiators and ESX iSCSI initiators is not supported.
ESX iSCSI initiators require RDM files to provision a LUN, but Microsoft iSCSI Software initiators do not have this requirement.
VMware limitations
RDMs are not supported on an NFS datastore; however, you can store RDMs in any connected VMFS datastore if the virtual machine is stored on NFS.
MPIO is not supported in a guest OS.
Windows Server 2008 failover clustering is not supported using ESX iSCSI RDM LUNs.
RDM LUNs larger than 2 TB are not supported.
IA64-bit operating system is not supported as a guest OS.
The second section (VMware limitations) is the key part where it states that MPIO is not supported in a guest OS. I think NetApp is suggesting that this is a VMware limitation, as I said I can't see why there would be limits from the storage perspective.
Thanks