There are some nice automations that come with the system but are a bit buried.
1. Assign Computer Ownership to the Primary User
2. Inventory to Asset Synchronization (ie Manufacturer, Model, and Serial Number)
3. Update Network Resource Location
On this last one you need to assign subnets to locations. This is done by editing a Location.
The three tasks listed above are found under Manage > Jobs and Tasks > System Jobs and Tasks > Service and Asset Management > CMDB.
Sandy