You may submit a file via scan and deliver or by excluding the original location of the sample and restoring it, then using the submission site below.
To submit a file directly from the Quarantine of Symantec Endpoint Protection:
Title: 'How to submit file(s) from quarantine using the new user interface within Symantec Endpoint Protection 11.0'
Document ID: 2007031308253048
> Web URL: http://service1.symantec.com/SUPPORT/ent-security.nsf/docid/2007031308253048?Open&seg=ent
To create exceptions for the original location of the file in Symantec AntiVirus Corporate Edition to restore from Quarantine and manually submit the file:
Title: 'Excluding specific drives and folders from Symantec AntiVirus scans'
Document ID: 2002092413394848
> Web URL: http://service1.symantec.com/SUPPORT/ent-security.nsf/docid/2002092413394848?Open&seg=ent
To manually upload a file that is being flagged as a threat and you see as a false positive to Symantec Security Response, please follow the manual submission process at the following URL:
https://submit.symantec.com/gold/
(If you do not have a Technical Contact Id, call Symantec Tech Support... Ask for the same...)
Few More Articles:
Title: 'Common loading points for viruses, worms, and Trojan horse programs on Windows NT/2000/XP/2003'
Document ID: 2001060517115206
> Web URL: http://service1.symantec.com/SUPPORT/ent-security.nsf/docid/2001060517115206?Open&seg=ent
Title: 'Common loading points for viruses, worms, and Trojan horse programs on Windows 98/95/3.1x'
Document ID: 1999052415383948
> Web URL: http://service1.symantec.com/SUPPORT/ent-security.nsf/docid/1999052415383948?Open&seg=ent