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In SEP 12.1 RU2 Symantec has released new feature i.e. ELAM (Early Launch Anti-Malware Driver)
arly launch anti-malware (ELAM) protects client computers from threats that load at startup. Symantec Endpoint Protection includes an early launch anti-malware driver that works with the Microsoft early launch anti-malware driver to provide the protection. The settings are supported on Microsoft Windows 8.
The early launch anti-malware driver is a special type of driver that initializes first and inspects other startup drivers for malicious code. When the Symantec Endpoint Protection driver detects a startup driver, it determines whether the driver is good, bad, or unknown. The Symantec Endpoint Protection driver then passes the information to Windows to decide to allow or block the detected driver.The Symantec Endpoint Protection settings provide an option to treat bad drivers and bad critical drivers as unknown. Bad critical drivers are the drivers that are identified as malware but are required for computer startup. By default, Windows allows unknown drivers to load. You might want to select the override option if you get any false positive detections that block an important driver. If you block an important driver, you might prevent client computers from starting up.
The Windows early launch anti-malware driver must be enabled for the Symantec Endpoint Protection settings to take effect. You use the Windows Group Policy editor to view and modify the Windows ELAM settings. See your Windows 8 documentation for more information.
Path: SEPM --> Virus & Spyware Protection --> Edit assigned Policy --> Protection Technology --> Early Launch Anti-Malware Driver
Adjusting the Symantec Endpoint Protection early launch anti-malware (ELAM) options
http://www.symantec.com/docs/HOWTO81106
Reference: https://www-secure.symantec.com/connect/articles/whats-new-sep-121-ru2
If you are looking for specific tools then SERT and Symantec power eraser can help you.
Power Eraser: http://www.symantec.com/theme.jsp?themeid=spe-user-guide
SERT: http://www.symantec.com/docs/TECH131732