1) If the software is digital signed, you can create an exception based on this.
2) You can send this peace of software to Symantec for Whitelisting, if it is publica available, only a link is necessary.
3) Did you checked that the client has the policy (policy serial number) which is assigned to this group?
4) You can made a prompt for Unproven Files, that the User decides, if he need the Software.
5) You can adjust the level for Reputation from 5 (default) to 2 or 1.