Based on the Microsoft Knowledge Base article (
http://support.microsoft.com/kb/955926/en-us) ,
Thumbs.DB is a thumbnail cache created by Windows when browsing files using Windows Explorer.
In case you need to disable the Thumbs.db restoration:
1. In Explorer, go to Tools -> Folder Options or open the Folder Options icon in the Control Panel.
2. Choose the View tab, and turn off the Do not cache thumbnails option.
3. Click Ok.
You can also change this setting in the Registry:
1. Open the Registry Editor (regedit.exe).
2. Navigate to
HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer\Advanced.
3. Double-click the DisableThumbnailCache value, or go to Edit -> New -> DWORD value to create a new value by that name.
4. Enter 1 for its value.