I just discovered an issue with Symantec Endpoint Protection 11.0.4 causes issues with DFSR Replication.
Apparently Outlook Auto-Protect causes email attachments that are saved to have the hidden "Temporary File" attribute set. DFSR doesn't replicate files with the temporary file attribute by design. Because of this, any user who saved a file from Outlook to our file servers was unable to replicate those files between offices.
These Links explain the DFSR issue:
Is this a known SEP issue? Are you planning to fix this Symantec?
I've since disabled Outlook Auto-Protect, though any help would be appreciated