Not really sure what you actually want to know.
But a how to configure can be found here.
As to configuring client systems, the only time you have to configure anything on a client system is with explicit proxy.
And for a HA environment you'd use the VIP address instead of the Proxies interface IP address.
For transparant proxy there's nothing you configure on the client, it's totally oblivious to the fact that there is a proxy anywhere..