Hello ,
In this case you can set up a new SEPM 12.1 and that point all clients to new server.
How to point Symantec Endpoint Protection(SEP) clients to a new Symantec Endpoint Protection Manager after you have either uninstalled, are going to decommission or replace the Existing Primary Symantec Endpoint Protection Manager (SEPM).
http://www.symantec.com/business/support/index?page=content&id=TECH92556
SEPM 12.1 can managed SEP 11.x clients as well .Once you have all clients reporting to new server ,you can upgrade clients from SEPM .
Upgrade client software
NOTE: Clients that are Group Update Providers must be upgraded first (Group Update Providers are not a feature of Small Business Edition).
Review applicable steps in Steps to prepare computers to install Symantec Endpoint Protection 12.1 client, and choose from available methods to upgrade clients to Endpoint Protection 12.1:
• AutoUpgrade*--assign client packages to groups in the Manager console, either manually or by using the Upgrade Groups Wizard.
• Permit product updates in LiveUpdate Settings policy for a client group in the Manager console.*
• Local installation from product disc.
• Run the Client Deployment Wizard from the Manager console. It will walk you through the creation of a client package that can be deployed via a weblink and email, remote push, or saved for later local installation or deployment using third-party tools.
* Methods marked with an asterisk are not available in Small Business Edition