We are using an On-Premise Full Web Isolation Virtual Appliance, Demo Edition installed as a Proxy and Threat Isolation Engine and all the web functionality is working fine. ( Isolation - Block - Authentication - Logs & Reports ).
Can this Threat Isolation Platform being used as the Mail Isolation appliance URL refered in the Symantec Mail Gateway as the Email Threat Isolation Prepend value field, that redirects the browser to your Symantec Email Threat Isolation appliance :
For example:https://server-threat-isolation.mycompany.com/?url=
Using this syntax, the following error appears when the URL link is opened :
Cannot GET /?url=www.symantec.com