You can do it at the APPL level. That will give you the option to name your variable whatever you want (I just used FILEPATH as an example). You could set as many as you need at the top of the app, then "plug" them in to your file watcher definitions as you go. So, to expand on this a little:
APPL MYAPP POST OLDEST
FILE1 = '/super/long/260/plus/character/path/to/the/file/you/want/to/watch1.xml'
FILE2 = '/super/long/260/plus/character/path/to/the/file/you/want/to/watch2.xml'
FILE3 = '/super/long/260/plus/character/path/to/the/file/you/want/to/watch3.xml'
FILE4 = '/super/long/260/plus/character/path/to/the/file/you/want/to/watch4.xml'
FILE5 = '/super/long/260/plus/character/path/to/the/file/you/want/to/watch5.xml'
FILE_TRIGGER MY_FILE_TRIGGER_1
AGENT myagent
RUN DAILY
FILENAME FILE1 CREATE
RELEASE (MYJOB1)
ENDJOB
FILE_TRIGGER MY_FILE_TRIGGER_2
AGENT myagent
RUN DAILY
FILENAME FILE2 CREATE
RELEASE (MYJOB2)
ENDJOB
FILE_TRIGGER MY_FILE_TRIGGER_3
AGENT myagent
RUN DAILY
FILENAME FILE3 CREATE
RELEASE (MYJOB3)
ENDJOB
FILE_TRIGGER MY_FILE_TRIGGER_4
AGENT myagent
RUN DAILY
FILENAME FILE4 CREATE
RELEASE (MYJOB4)
ENDJOB
FILE_TRIGGER MY_FILE_TRIGGER_5
AGENT myagent
RUN DAILY
FILENAME FILE5 CREATE
RELEASE (MYJOB5)
ENDJOB
JOB_MYJOB1
RUN DAILY
ENDJOB
(RINSE, REPEAT)
Legal Disclaimer: Like I said, my syntax may be way off. I suggest you consult DocOps and read up on variables.
-Jonathan