Hello Travis,
This is a brief summary of what I just sent to you over the Customer Support ticket you opened.
Release 12.1 introduced two new features that utilizes SYSPLEX technologies and they are:
SYSPLEX Variables and SYSPLEXSCOPE Parameter
Under release 12.2 the new "System State Manager Global Application Version 2 (SSMGAV2)" can setup to use SYSPLEX Variables.
Good to hear you will be running multiple systems under your SYSPLEX complex. You need to run a CA OPS/MVS main region and OSF Servers (as well other tasks like USS Servers) for automation purposes on each system.
I hope the community can share with you more info but consider review this KD about your rule sets across systems:
How to create system-unique rule data sets for CA OPS/MVS Event Management and Automation?
Hope this helps Travis
Regards, Cesar