You won’t be able to do a full database load once you’ve installed a newer version of Spectrum. You can only do a models only load after the install, so you’ll lose your catalog (which may contain attributes created from imported mibs and/or spectrwatches etc). It’s still supported, but your catalog will be reverted.
If you want to keep your entire SSdb (models and catalog), you can use the migration method for Spectrum (take your unzipped SSdb file, rename it to dbsavefile.SSdb, put it on the new box in the /SS directory, and then run the 10.1 install on top of it).
Cheers
Jay