Hi Richard - To confirm your questions/statemens
Statement - Increase RequestTimeout a significant amount from the default of 60 to, say 120. Observe results at 120 and reduce RequestTimeout 10 seconds at a time until the "optimal" value is determined.
Answer - Yes this is reasonable
Question- Is there an upper limit to RequestTimeout that you would consider unreasonable?
Answer -Throwing this question around my fellow global senior team
Statement - Increase RequestTimeout in 10-second increments and stop when connections are no longer timing out under heavy load.
Answer - Yes, this is a good plan
Question- Do you have any anecdotes to share regarding the circumstances and results when you tuned RequestTimeout in an enterprise environment?
Answer - Can't remember if there is any documentation on this , but we can ask around .