Raj,
Is your Policy Server just 12.52 base version or is there any SP on top of it ? please specify exact version.
However, according to platform support matrix - SAP Portal Services :
"Windows 2016 with IIS 10 is supported from Webagent version 12.52 SP1 CR08 onwards." that being said there is caveat in the support matrix:
"CA SiteMinder12.52 Policy Server supports Web Agents at a higher CR (cumulative release) number than the Policy Server
provided both are the same level Service Pack"
What does it mean is, your policy server should be 12.52SP1 version minimum in order to support Win 2016 with IIS 10. If this is the case, you can go with latest version of webegent 12.52 SP1 CR09 (as of 8/9/2018).
Hope this helps !.
Regards
Ashok