For your awareness, if you have McAfee Endpoint Security 10.2.0 and use Software Delivery over Network Shares (NOS Delivery)--
Link to McAfee KB:
https://kc.mcafee.com/corporate/index?page=content&id=PD26758
Items of interest affecting ITCM:
1140210: Previously, accessing file shares located on servers running Endpoint Security caused delays.
1146894: Client systems no longer hang when opening an application on a network share.
If you see this error message while doing Software Delivery in ITCM...
"Job execution error, no access to software package library. Native OS error: 2 - The system cannot find the file specified.. [SDM228482]"
...this hotfix from McAfee may very well be the solution.
Brian Fontana, CA Support.