You are better off having a recent image of your machine(s), than you are of having "system restore" enabled. System restore is a copy of your system's configuration. Generally when you receive a threat, virus or other, it will reproduce itself into the "system restore" of the system volume. Enuring it's capability to restore itself.
Because of this, and that System restore is pretty compressed and, scan times can be increased as the system has 2 times as much data to scan.
As best practice, and very rarely used, system restore should be turned off. Just my 2 cents.