It's pretty common to NOT deploy NTP to servers. I do that in many cases for servers that see more than 20% link utilization on average during production hours. If the server is barely used/accessed, and has very little to no LAN traffic, I do enable NTP, or if the server is public facing in a DMZ, I do enable NTP.
In your case with iSCSI, you will want to probably disable NTP, or find a way to unbind those services from the actual adapter if possible. It escapes me if that is possible in SEP, I dont think so, so I would advise to just turn off NTP on the iSCSI enabled hosts.