I just finished woking at a vSphere project for a customer site. I tried working by the book when I created the vCenter instance as a VM according to VMware best practices. I also configured vDS with the binding requirement for the vCenter VLAN.
But I was really wondering would it really save the admin effort and time for both me and the customer to configure hosts with vDS if compared to vSS and host profiles? I personally think the latter saves more time and effort, specially when dealing with vCenter VMs, unless of course vCloud Director is a future objective for the customer.
What do you thinks guys? are there reasons to favor vDS that I might be missing here?