In my experience, i had issues with too slow disks (SATA 7200 RPM). This works fine with some VMs which don't need high performance, like dev/QA environment.
However, if your VMs need high performance like database servers, the disk speed it's a big concern. But this is just one among many concerns about the storage performance.
The cache size is also a big deal. If your SAN has a large cache and this is well configured, then the RAID configuration isn't so important. Otherwise, the RAID type would become in a critical aspect in order to get a good performance of your VMs.
The number of VMs on one datastore is important too. It's recommended to distribute the VMs on smaller datastores instead of group all the VMs on just one big datastore. This improve the load balancing of storage resources.
There are too many factors when you are troubleshooting a disk performance issue. All depend of the VMware infrastructure you are troubleshooting, the Storage device, and how you connect the ESX/ESXi hosts with the Storage device.
Regards / Saludos
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