Andy,
Config:
3 x Dell R710 running ESX4. Dell Equallogic PS4000E SAN connected via iSCSI. 2 x HP Procurve 3500yl-24G switches inbetween.
MPIO set up, pathing static through two VMKernel ports linked to two Pnics.
I have four errors reported on the VCenter this morning from two different hosts, all connection errors. They were at 00.34, 03.14, 04.25 and 05.14. All of these were on to a volume called SAN-ISO_STORE which I use to store .iso files, etc. At the time, none of my VMs had anything mounted from this store, so the problem is DEFINITELY not VM related.
As to the log, yes, there are Nop timeouts show at the relevant times. The file is attached, but the relevant entries are here as well:-
2009-11-19-00:34:01: iscsid: Nop-out timedout after 10 seconds on connection 4:0 state (3). Dropping session.
2009-11-19-00:34:04: iscsid: connection4:0 is operational after recovery (2 attempts)
2009-11-19-03:14:09: iscsid: Nop-out timedout after 10 seconds on connection 4:0 state (3). Dropping session.
2009-11-19-03:14:12: iscsid: connection4:0 is operational after recovery (2 attempts)
2009-11-19-05:14:08: iscsid: Nop-out timedout after 10 seconds on connection 4:0 state (3). Dropping session.
2009-11-19-05:14:12: iscsid: connection4:0 is operational after recovery (2 attempts)