I don't believe you can do that with RestAPI.
Everything you can do is listed here:
https://apidocs.symantec.com/home/saep------------------------------
John Owens
Principal Product Support
Symantec
United States
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Original Message:
Sent: 05-04-2020 02:55 AM
From: test test
Subject: Endpoint Protection Rest Api
How do I block md5 with application device control policy using the rest api?