I have a very large team, I would like to prevent team members from mistakenly editing each others stories. Can I limit story editing to only the story owner (and project admins)?
Permissions in Agile Central are not granular enough to be restricted in this manner. Anybody with at least editor permissions to the project that houses the story would be able to make changes. You can view the Revision History to see who made the change, and what it was though.