Hi,
I suppose you would like to install and configure IIS 10 Web Agent on Windows 2016. In this case, you must not use the installer:
RS92406 Siteminder Web agent 12.52 SP01 CR06.
Instead, please use another one of CR06 for IIS10:
RS95103 SiteMinder Web Agent 12.52 SP01 CR06 IIS10.
I hope this would help.
Regards,
Koichi Ikarashi